Cirrhosis, hepatitis infection and other causes can trigger liver fibrosis—a potentially lethal stiffening of tissue that, once begun, is irreversible. For many patients, a liver transplant is ...

In mice at least, scientists have found a way to stop and even reverse a deadly scarring of liver tissue called fibrosis If proven to work in people, it would be a major advance for patients battling ...

Fibrosis, or scarring, plays a major role in many diseases and is often accompanied by inflammation. Pulmonary fibrosis refers to scarring in the lungs, which damages lung tissue, making it harder for ...

but the literature on lingual gingival augmentation is scarce. The purpose of this paper is to report the outcomes of a case treated with an envelope flap combined with a hybrid soft tissue autograft ...

TGFβ1 is a central pro-fibrotic mediator in IPF. A better understanding of the molecular pathways activated by TGFβ1 in human lung tissue may facilitate the development of novel more effective ...

Joyce and her team applied an integrated multiomics approach to the scar tissue: mass spectrometry-based proteomics, single-cell RNA sequencing, and spatial transcriptomics. Given the fibrotic nature ...

Mice were either challenged with bleomycin or overexpressing a constitutively active transforming growth factor (TGF)β receptor I. Conclusions Our data identify TWIST1 as a central pro-fibrotic factor ...

Nov. 13, 2024 — The use of biologic and targeted therapies for children with juvenile idiopathic arthritis (JIA) surpassed more typical therapies in recent years, according to ...

Gum cancers develop within the tissues of your gums, rather than the lips, inner cheeks, or other parts of your mouth. The challenging part about gum cancer is that its early symptoms may mimic ...

Aug. 22, 2024 — Managing hard-to-treat respiratory illnesses like asthma and pulmonary fibrosis just got easier if a new drug-carrying molecule is as sneaky as its inventors ... COPD and BPD ...