Methods The study aims to elucidate the role of PET117 in CRC ferroptosis using cell, mouse and colorectal tumor models and investigate PET117’s regulation of CRC mitochondrial function through ...

A laboratory study provides evidence about how advanced age can be protective against cancer -- with implications for treating patients in different age groups.

By Dr. Chinta Sidharthan Researchers reveal how aging induces iron insufficiency, reducing stem cell function and tumor ...

2024 — A team of researchers has discovered that the tumor suppressor protein Prostate apoptosis response-4 (Par-4) can cause a unique type of cell death called ferroptosis in human glioblastoma ...

Hepatocellular carcinoma (HCC) is a significant global health issue, ranking as the sixth most prevalent malignancy and the ...

Cancer risk decreases in advanced age as cellular changes stabilize, offering hope and a deeper understanding of aging and ...

The TIME is a dynamic network composed of cancer cells, immune cells, and stromal components. During the early stages of tumorigenesis, the TIME ...

The TIME is a dynamic network composed of cancer cells, immune cells, and stromal components. During the early stages of tumorigenesis, the TIME attempts to eliminate abnormal cells through immune ...

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...

Making improvements? Take command of a career pursuit as the sun and Chiron harmonize. Stand behind your decisions. Now’s your chance! Your education and experience have prepared you for this ...