Hair loss significantly impacts patients' quality of life, and it may be nonscarring or scarring. Etiologically, hair loss ...

This study presents important findings on cold tolerance shared between hibernating and non-hibernating mammals, identifying a key molecule, GPX4, through multi-species genome-wide CRISPR screens. The ...

The Zoghbi lab had earlier identified TYK2—an enzyme that adds phosphate to Tyrosine groups—as a potential regulator of tau levels and that knocking down the TYK2 gene reduced tau levels in ...

So phosphate levels are to be monitored regularly. Pralsetinib should not be given along with inhibitors or inducers of CYP3A4. Reduce dose from 400 mg and 300 mg to 200 mg and from 200 mg to 100 ...

Department of Chemical Sciences and Technologies, University of Rome Tor Vergata, Via della Ricerca Scientifica, Rome 00133, Italy Department of Chemical Engineering and Biotechnology, University of ...

They found that a specific enzyme — a fatty acid amide hydrolase (FAAH) — from Faecalibacterium prausnitzii significantly influences immune function pathways through its role in hydrolyzing ...

These include the inhibition of transporters and catabolic enzymes (inducer inclusion) and the inactivation of transcription factors (induction prevention). CCR has a key role in the expression of ...

Biochemists from the National University of Singapore (NUS) have discovered a new subclass of trifunctional enzymes in gram-positive bacteria, which play a critical role in the biosynthesis of an ...