an essential bacterial enzyme and a major target for antibiotics (1 Trusted Source New mechanism in bacterial DNA enzyme opens pathways for antibiotic development Go to source). This enzyme ...

Among children treated with an oral agent, the recurrence rate was 16/42 (38.1%) following penicillin or amoxicillin and 10/36 (27.8%) following a beta-lactamase resistant agent (adjusted odds ...

Quick treatment with antibiotics is considered essential, as the disease can cause death within a matter of hours. But this January, an isolate that produced a beta-lactamase enzyme (which breaks down ...

Among children treated with oral penicillin or amoxicillin ... This rate is higher than observed in children treated with a beta-lactamase resistant agent, although the associated risk estimate ...

a vital bacterial enzyme and key antibiotic target. This enzyme, present in bacteria but absent in humans, plays a crucial role in supercoiling DNA, a necessary process for bacterial survival.

The research could aid in the development of next-generation antibiotics that are more precise and effective in stopping bacterial infections. DNA gyrase is a bacterial enzyme that introduces ...

The problem is that methicillin belongs to a broader family of antibiotics, beta-lactams, and MRSA has become resistant to almost all of them. “MRSA can sometimes be treated with other antibiotics, ...

Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Centre have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic ...

Department of Pharmacy, Saarland University, Campus E8.1, Saarbrücken D-66123, Germany Department of Pharmacy, Saarland University, Campus E8.1, Saarbrücken D-66123, Germany Helmholtz Institute for ...