In animal cells, DNA can be modified by methylation of cytosine residues in CpG dinucleotides, and the N-terminal tails of histone proteins are subject to a wide range of different modifications ...

DNA methylation is the covalent addition of methyl groups to DNA bases, typically the cytosine of CpG dinucleotides. It is catalyzed by methyltransferase enzymes using a S-adenosyl methionine ...

PE is thought to result from a combination of factors, including inflammatory cytokines, trophoblast dysfunction, and environmental influences, which may trigger epigenetic changes, particularly DNA ...

More importantly, studies of DNA methylation and histone modification using NGS technologies have yielded new discoveries and improved our knowledge of human biology and diseases. The concept that ...

Each of these bricks is made up of 24 nucleotides (including cytosine sites for methylation) and encodes one bit of information, creating a stable and readable set through advanced sequencing ...

A new study introduces a method to infer DNA methylation patterns in non-skeletal tissues from ancient DNA, offering insights into human evolution, particularly brain function. Using an algorithm with ...

Each of these bricks is made up of 24 nucleotides (including cytosine sites for methylation) and encodes one bit of information, creating a stable and readable set through advanced sequencing ...

Methods: Nasopharyngeal Carcinoma tissues from 3 patients and non-cancerous nasopharyngeal tissues from 3 individuals, all from Fujian Cancer Hospital, were sequenced for m6A methylation. These were ...