Teos Therapeutics (ITOS) announced the presentation of clinical, translational, and preclinical data from its adenosine A2A receptor ...

Cholesterol restriction-mediated SREBP1 activation induces noncanonical type I IFNs, including IFN-ω and minor IFN-α subsets, ...

Immune checkpoint inhibitors may heighten cardiovascular risks by altering immune interactions in atherosclerotic plaques, ...

2020). In the complex signaling transduction process, Protein kinase C (PKC) is a key effector molecule within the G protein-coupled receptor system. Figure 2. Oxidative stress pathways in CI-AKI. CM ...

Cite this: TNF Signaling Inhibition in the CNS: Implications for Normal Brain Function and Neurodegenerative Disease - Medscape - Oct 17, 2008.

Innate immune signaling pathways of TLRs, IL1-Rs, and TNFRs ... as well as reduced transcription of chemokines CCL2 (MCP1), CCL3 (MIP1α), and chemokine receptor CX3CR1. Consequently, the infiltration ...

This study presents a valuable finding on a potential signaling pathway responsible for the direct effects of nicotine on intestinal ... and Notch signaling in ISCs via α7-nicotinic acetylcholine ...