Here, we used deep full-length single-cell RNA-sequencing to distinguish post-mitotic cone and rod developmental states and cone-specific features that contribute to retinoblastomagenesis. The ...

In this study, our results uncover the function and mechanism of CHMP5 in the regulation of cell senescence and bone formation in osteogenic cells. Deletion of Chmp5 causes endolysosomal dysfunction ...

Planegg/Martinsried. Medigene AG (Medigene or the “Company”, FSE: MDG1, Prime Standard), an oncology platform company focused on the research and development of T cell receptor (TCR)-guided therapies ...

This handbook contains a comprehensive collection of protocols to streamline imaging workflows and ensure reproducible ...

You probably learned about organelles, those little “organs” inside cells that form compartments with individual functions. For example, mitochondria produce energy, lysosomes recycle waste ...

Did you know that every single living thing is made up of teeny, tiny unit structures? You have more than 75 trillion of them in your body – they’re called cells and they are amazing! Today we are ...

SFTSV infection is characterized by suppressed host innate immunity, proinflammatory cytokine storm, failure of B-cell immunity, and robust viral replication. m6A modification has been shown to play a ...

Stem cells are specialized cells that have the potential to develop into not one but many different types of cell. They are unlike any other cell for three specific reasons: They are unspecialized, ...

In this study, the research group proposed a new system in which the growth-factor secreting rat liver cells would be co-cultured or cultured together with the modified cyanobacteria, and the ...

The researchers discovered that the medium remaining after culturing these liver cells (or the supernatant) contains growth factors, and can support muscle cell growth without the use of serum.