PPP1R2, also known as Inhibitor-2, is a regulator of PP1 with an elusive function. Here, the authors show that PPP1R2 functions as an additional subunit of a subset of PP1 holoenzymes, thereby ...
Tumor cells transform fibroblasts into cancer-associated fibroblasts, which have an important immunosuppressive activity on which growth, invasion, and metastasis depend. These activated fibroblasts ...
Resembling a seahorse, as its name implies from the Greek words 'hippos' (horse) and 'kampus' (sea monster), the hippocampus is a brain region crucial for memory formation. But until recently, ...