HIV and treatments. On left, the HIV virus binds to CD4 T cell CD4 receptor, which will allow the ... [+] co-receptor CCR5 to melt and release the viral RNA into the cytoplasm. After reverse ...

(c) Glucocorticoid receptor (GR) protein immunoblot of whole thymus or purified CD4+ thymocytes. Antibodies to the glucocorticoid N terminus (top two panels) and DNA binding domain region (bottom ...

Studies over more than a decade have generated a picture of how the external Env subunit (gp120) interacts first with the primary receptor (CD4) and then with a co-receptor (a chemokine receptor ...

Other targets for entry inhibitors include two co-receptors on the cell surface—CCR5 and CXCR4—which together with CD4 mediate virus binding and membrane fusion 3. As CCR5, but not CXCR4 ...