Synthetic suppressor T cells could improve treatment for organ transplants, type 1 diabetes, and other autoimmune conditions.

In the resting state, the paucity of CD4+ T cells in the submucosa may be ... HIV signaling through TLRs and other pattern recognition receptors and how this affects pDC functions, are also ...

Before fusion of the HIV viral envelope and host cell membrane can occur, an HIV glycoprotein complex consisting of glycoproteins gp41 and gp120 must bind with the CD4 receptor on the membrane of ...

Nerve growth factor receptor TrkA (in green) and co-receptor NRP1 (in purple) are coexpressed in the same nerve cells in mice. Researchers at the NYU Pain Research Center have found a new receptor ...

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but there is high variability in average expression levels between individual receptor and cell types. Substantial co-expression is found between receptors across clades, from different classes, and ...

Polypharmacy in patients with HIV influences perceived cognitive deficits and physical frailty through an anticholinergic and ...

Emboldened by technological advances and a deeper knowledge of glioblastoma, Merck, Kazia Therapeutics, CorriXR Therapeutics ...

The advent of T-cell receptor (TCR) sequencing offers a transformative lens to unravel these challenges, spotlighting tumor-immune interactions and adaptive immune mechanisms pivotal to advancing ...

These results support previous observations that autophagy is induced in B cells in the absence of co-stimulation, a situation that leads to cell death.12 Autophagy therefore presents a potential ...