This review summarizes the mechanisms of action and clinical activity ... and the proteasome inhibitor bortezomib. [1] IMiDs are structural and functional analogs of thalidomide that have potent ...

Mechanism of action describes the process by which a molecule, such as a drug, functions to produce a pharmacological effect. A drug’s mechanism of action may refer to its effects on a ...

The American Journal of Managed Care provides insights into the latest news and research in managed care across multimedia ...

“Patients with multiple myeloma need treatment options after first relapse that are efficacious, readily accessible and have novel mechanisms ... dexamethasone versus Velcade plus Pomalyst ...

Karyopharm Therapeutics Inc. (Nasdaq: KPTI ), a commercial-stage Pharmaceutical company pioneering novel cancer therapies, today announced abstracts detailing selinexor data have been selected to be ...