The LAR is associated with prolonged airway hyperresponsiveness and increased eosinophilia. Benralizumab, a monoclonal antibody targeting the interleukin-5 receptor alpha (IL-5Rα), induces ...
The basophil activation test (BAT) is not a primary diagnostic tool; it is a test complementary to the skin test and quantification of allergen-specific IgE. The BAT is currently mostly applied in ...
Preclinical studies demonstrate a cardioprotective role of eosinophils in acute myocardial infarction. Yet clinical studies show conflicting correlations between blood eosinophil counts and acute ...
Mast cells and basophils share many characteristics, such as morphology, surface expression of FcεRI, and granule storage of histamine. Mast cells are distributed to nearly all vascularized tissues ...
Allergen-specific antibody test, basophil activation assay, measurement of inflammatory mediators released, (i.e., mast cell tryptase) and lymphocyte stimulation studies are other tests used as ...
Objective The present study tested the hypothesis that arterial stiffness will be elevated across overall and specific inflammatory disorders compared with an inflammation-free comparison group.