Brain-derived neurotrophic factor (BDNF), a crucial protein, plays a significant role in neuron growth and brain development. It is essential for mental processes, learning, and memory functions.

在大脑的神经元中，iSPN在亨廷顿氏病中受到特别的影响，并可能导致多巴胺失衡和运动问题。 尽管研究表明脑源性神经营养因子(BDNF)-原肌球蛋白受体激酶B （TrkB）信号传导受损与亨廷顿氏病有关，但破译其确切作用一直具有挑战性。了解BDNF-TrkB信号的改变 ...

“Further exploration of these pathways offers a promising avenue for developing personalized therapeutic ... Carriers of at least one SNP in the HMOX1 gene (rs2071747) and the BDNF gene (rs6265) had ...

Quebec has hit the breaks on two major permanent resident pathways. Effective immediately, Quebec is no longer accepting applications for the Quebec Experience Program - Quebec Graduates (PEQ - ...

Contrary to the belief that the path to sustainable development is increasingly out of reach, the results show that humankind has a variety of pathways to depart from its current unsustainable ...

Using a common model for PSD, these studies collectively implicate the BDNF-TrkB signaling pathway and the hippocampus as a target for nutraceutical treatments. Because of the prevalence of poststroke ...

The researchers identified that problems with specific neurons in the brain, called indirect pathway spiny projection neurons (iSPNs), which are the initially ... This study uncovers a functional link ...

Research shows new brain pathways in the striatum modulate dopamine, linking movement control to emotional decisions, enhancing our understanding of motivation. Credit: SciTechDaily.com MIT ...

Agencies have a new way to connect with qualified early-career workers and move them from the Pathways Program into full-time federal jobs. Two new “talent programs” on USAJobs, which the Office of ...