Antisense therapy is a form of treatment that uses antisense oligonucleotides (ASOs) to target messenger RNA (mRNA). ASOs are capable of altering mRNA expression through a variety of mechanisms, ...

The antisense oligonucleotide company also received a big cash injection in March 2024 after a $100 million private placement. Sarepta Therapeutics has a pipeline of programs in various stages of ...

Ionis has committed to a phase 3 programme for its antisense therapy for rare genetic disorder Angelman syndrome, just weeks after Biogen decided against exercising an option to license the drug.

Bio-Path’s lead drug candidate, prexigebersen (BP1001), is an antisense therapy targeting the Grb2 protein. This protein plays a key role in cancer cell survival and proliferation, making it a ...

The oligonucleotides market has gained significant traction in recent years due to its critical role in molecular biology, genetics, and therapeutics. Oligonucleotides, short DNA or RNA molecules, are ...

GSK’s antisense-based drug for chronic hepatitis B (CHB), bepirovirsen, will get a rapid six-month review from the FDA when it is filed for approval, said the drugmaker this morning. The fast ...

New therapies that are less intrusive but more lasting than current interventions promise to arrest and even reverse neurodegeneration.

Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

In a Type B meeting, the FDA signified that it will allow uniQure to use a natural history control, the composite Unified ...

Couples therapy is a type of therapy that aims to help romantic partners address relationship conflicts, improve communication, and increase affection and empathy for one another. Couples ...