"I take medication thrice a day and the doctor has advised me not to contemplate getting pregnant as it can be fatal for both ...

Primary antiphospholipid syndrome (PAPS) is a clotting disorder attributed to autoreactive antibodies produced by B cells. Here the authors show, using single cell omics and B cell repertoire data ...

Background: Antiphospholipid antibodies (aPL) trigger inflammation ... of aPL and atherosclerotic cardiovascular risk in a diverse population without established cardiovascular disease or ...

Antiphospholipid antibody syndrome (APS) may lead to pulmonary hypertension, a lethal complication of chronic pulmonary thromboembolism. There are few viable treatment options for pulmonary ...

Other studies include: the development of a precision immunotherapy to target harmful B cells in Antiphospholipid Syndrome (APS) patients; the discovery of innate signaling pathways crucial in ...

Other studies include: the development of a precision immunotherapy to target harmful B cells in Antiphospholipid Syndrome (APS) patients; the discovery of innate signaling pathways crucial in ...

The disorder – driven by type 2 inflammation characterised by an antibody-based immune response – causes hard lumps or nodules to form on the skin that are so itchy they can lead patients to ...

Furthermore, these antibodies seemed to specifically affect the sebaceous glands and had little or no impact on other components of the skin such as the adipocytes and the interfollicular epidermis.