Initially intended to mimic multiple sclerosis (MS) in animal models, these compounds unexpectedly led to a breakthrough drug ...

Cardiovascular health is a crucial topic in modern medicine, and the use of certain medications can have significant ...

The utility of diuretic therapy in preventing heart failure is now well accepted and it is possible in this trial that doxazosin was not a drug that caused heart failure but rather one that simply ...

Aldosterone is an important mediator in the pathogenesis of heart failure, and increased plasma aldosterone levels are associated with a poor prognosis. Aldosterone-receptor blocking drugs can ...

Some of the top heart failure research looked at statins and semaglutide for heart failure with preserved ejection fraction, ...

Progress in assessing cardiovascular risk and identifying early prevention opportunities, improvements in treating heart failure, new therapies for bleeding strokes, strategies for reducing the ...

Aims: Non-steroidal anti-inflammatory drugs have been associated with increased risk of congestive heart failure (CHF). We aimed to assess the impact of treatment with etoricoxib or diclofenac on ...

COMET-HF (Confirmation of Omecamtiv Mecarbil Efficacy Trial in Heart Failure) is a confirmatory ... that the FDA has accepted the company’s new drug application (NDA) for lead pipeline candidate ...