We conducted a systematic review and meta-analysis to evaluate the abscopal effect and its immune microenvironment influence in solid tumor animal models treated with Uncombined with immunotherapy.

Tumor volume was measured and calculated using the formula: volume = length × width² × 0.5. All animal experimental procedures ... in vivo effect of squalene in the KPC syngeneic mouse model, and ...

14, 2024 — Researchers have developed a three-dimensional mathematical model of prostate ... into how prostate cancer spreads or ... Inflammatory Cells in Tumor Microenvironment Promote the ...

18, 2024 — Research has uncovered a vulnerability in prostate cancer animal models that starves prostate ... Inflammatory Cells in Tumor Microenvironment Promote the Transformation of Prostate ...

The study used molecular, cellular, and animal models to investigate how ... systems to analyze the interaction between tumor cells and their microenvironment, while also exploring therapeutic ...

Researchers want trustworthy, human-relevant models. Integrating automation and AI into organoid development workflows—or opting for validated off-the-shelf models—are a few innovative and accessible ...

Our previous reports have focused on the tumor microenvironment in liver cancer ... has been largely ineffective across multiple cancer models, suggesting that CXCR4 targeting should be tested ...

Share on Pinterest Dietary fructose may contribute to cancer tumor growth, a study in animal models suggests. Image credit: Rob Webb/Getty Images. Fructose is a natural sugar found in fruits ...

"After constructing AAVs with a cancer-specific promoter and a cancer-targeting nanoparticle, we found this therapy is very powerful to treat multiple cancers." Experiments in mouse models showed ...

Overall, this fundamental study identified a novel role of NOLC1 in regulating p53 nuclear transcriptional activity and p53-mediated ferroptosis in gastric cancer. The evidence supporting the ...