Both the N- and C-terminal helices are highly amphipathic, and the burial of hydrophobic residues will induce helical structure in these amphipathic sequences. It is likely, therefore, that long ...
CPP are usually short cationic or amphipathic peptides, able to interact with the negatively-charged biological membranes. One interesting natural compound acting as CPP is melittin which composes 50% ...