Background: Although sucrose non-fermenting 1-related kinase (SNRK) in endothelial cells (EC) has a critical role in anti-inflammation and anti-fibrosis in the kidney, whether SNRK controls EC ...

Both infiltrating immunoinflammatory cells and adipocytes play critical roles in the modulation of metabolic homeostasis, so it is important to understand factors that regulate both adipocyte and ...

FRIDAY, Nov. 1, 2024 (HealthDay News) -- Cirrhosis, hepatitis infection and other causes can trigger liver fibrosis -- a potentially lethal stiffening of tissue that, once begun, is irreversible.

What is cystic fibrosis liver disease? Liver disease associated with cystic fibrosis (CF) has been increasingly diagnosed during recent years, most likely due to the combined effect of systematic ...

Expression was boosted for genes involved in lipid metabolism pathways and in the inactivation of inflammation and fibrosis in the livers of bFKB1 mice. Using microscopy, the researchers observed ...

WASHINGTON, DC—An early aortic valve replacement (AVR) strategy with either TAVI or surgery fails to lower the risk of all-cause mortality or unplanned aortic stenosis-related hospitalizations in ...

There are also stark differences in the causes of these conditions. Causes of Fibrocystic Breast Changes Hormonal fluctuations trigger two fibrocystic changes in your breasts: cysts (fluid-filled sacs ...

we identified adipocyte enhancer binding protein (AEBP1) to be significantly upregulated in activated fibroblasts. AEBP1 has been shown to play a crucial role in fibroblast activation following injury ...

Moreover, FGF21 decreased lipid- and scar-associated macrophages, which correlated with less hepatic fibrosis as demonstrated by reduced collagen accumulation. Collectively, hepatic FGF21 ...