Older patients with PAH frequently have a more complex clinical presentation compared with younger patients. In patients with pulmonary arterial hypertension (PAH), all models derived from the Swedish ...

IgG4-RD of the breast is rare but should be considered a differential diagnosis if biopsies rule out cancer. Immunoglobulin G4-related disease of the breast (IgG4-BD) is rare but should be considered ...

A multidisciplinary approach is crucial in transitioning high-risk prostacyclin therapies in PAH. A successful transition from high-dose intravenous epoprostenol to high-dose subcutaneous treprostinil ...

At present, PAH remains an incurable and relatively costly disease, particularly for patients with CHD. MiRNAs can serve as promising alternatives to certain protein biomarkers, which often exhibit ...

Study results revealed a significantly lower rate of flares and a higher rate of remission among patients treated with inebilizumab. A new study has found that inebilizumab, a humanized anti-CD19 ...

PBC significantly increased the abundance of the class Bacteroidia, order Bacteroidales, and phylum Bacteroidetes and decreased the abundance of the genus Lachnospiraceae UCG010. The authors concluded ...

Researchers sought to determine the validity and safety of remote digital monitoring the 6-minute walk test in patients with PAH. The 6-minute walk test (6MWT) has become one of the most important ...

While IgG4-RD can affect various organs in the body, approximately one-fifth of patients present with ophthalmic involvement. Immunoglobulin G4-related disease (IgG4-RD) is a rare but largely ...

Patients whose ATX levels were above the threshold had a cumulative liver-related events incidence of 33.3% Novel biomarkers could help predict disease progression for patients with primary biliary ...

Progress concerning second-line choleretic drugs is evident, but long-term beneficial outcomes of new agents should be estimated in phase IV trials. The updated concepts of treatment endpoints and new ...

This suggests that adiponectin may serve as a potential biomarker for identifying advanced liver cirrhosis. Levels of adiponectin are significantly elevated in patients with primary biliary ...

Results showed that HD mice had lower NRXN1 mRNA expression than wild-type mice and that NRXN1 levels were higher prior to symptom onset. Neurexin 1 (NRXN1) appeared to be reduced in post-onset ...