Background Bronchoalveolar lavage (BAL) is essential in determining the efficacy of novel therapies in alpha-1 antitrypsin deficiency (AATD). These require initial proof-of-concept demonstration that ...

Correspondence to Professor Weihong Chen, Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ...

Rationale Endoscopic lung volume reduction improves lung function, quality of life and exercise capacity in severe emphysema patients. However, its effect on the diaphragm function is not well ...

This paper contains an analysis and appreciation of one of Moses Maimonides' authentic medical works, his Treatise on Asthma. After a brief biographical section, passages from the work are cited and ...

Background Childhood interstitial lung disease (chILD) encompasses a group of rare heterogeneous respiratory conditions associated with significant morbidity and mortality. Reports suggest that many ...

1 Department of Respiratory Medicine, Division of Immunology, Infection and Inflammation, University of Glasgow, Glasgow, UK 2 Department of Immunology, Division of Immunology, Infection and ...

BACKGROUND The bronchiolitis obliterans syndrome (BOS) remains the major constraint on the long term success of lung transplantation. Neutrophils have been associated with fibrosing lung conditions ...

2 Centre for Evaluation and Methods, Wolfson Institute of Population Health, Queen Mary University of London, London, UK 3 Division of Immunology, Immunity to Infection and Respiratory Medicine, ...

Introduction There has been a marked increase in vaping in the UK since 2012 and in children between 2018–2021. Anecdotal reports from those working directly with children and young people indicate ...

Asthma exacerbations are common. They account for a significant morbidity and contribute a disproportionate amount to the cost of asthma management. The optimal strategies for the prevention of asthma ...

Introduction Oral pirfenidone reduces lung function decline and mortality in patients with idiopathic pulmonary fibrosis (IPF). Systemic exposure can have significant side effects, including nausea, ...

S Baudouin, S Blumenthal, B Cooper, C Davidson, A Davison, M Elliot, W Kinnear (Chairman), R Paton, E Sawicka, L Turner (Secretary) Non-invasive ventilation (NIV) refers to the provision of ...