科学家发现,转运 RNA (tRNA) 能够决定信使 RNA(mRNA)在细胞中的寿命,导致某些 mRNA 被稳定保存并翻译成更多的蛋白质,而另一些 mRNA 则被降解,从而限制蛋白质的生成量。
On the other end, Walgreens Boots Alliance (WBA), Moderna (MRNA), and Dollar Tree (DLTR) are among the worst performers. Sector-wise, financials (XLF), communication services (XLC), and utilities ...
Given their non-migratory nature within the mineralized matrix, their unique dendrites are crucial for cell-to-cell communication in response to both intracellular and extracellular stimuli, such as ...
To create A1 lipid nanoparticles for delivering mRNA to target cells, scientists at the University of Pennsylvania used A3 coupling. A3 refers to the amine–aldehyde–alkyne coupling reaction ...
In that respect it follows a similar model to Merck's takeover of AmpTec, another CDMO that uses a PCR platform to make mRNA drugs, for an undisclosed sum last year. Outsourcing services are on of ...
CureVac and partner GSK are, meanwhile, also developing an mRNA-based flu vaccine, but are a little further back in development, as their shot is in phase 1 testing.
Type 2 diabetes (T2D) and obesity (OB) are associated with chronic low-grade inflammation and increased fracture risk. In vitro studies showed that inflammation induces bone erosion and inhibits bone ...
That clinical severity is a function of Pmp22 mRNA expression is suggested by the ... position of primers used for quantitative real-time PCR and genotyping. Transcripts containing exon 1A ...
According to the VDH website, only about 9% of Vermonters have received the booster, with the highest rate in Addison and ...
磷酸果糖激酶血小板型(PFKP)是糖酵解途径中的一个关键限速酶,它的异常表达通过改变多种生物学功能在多种人类癌症的发展中起着至关重要的作用。然而,PFKP在HNSCC中作用的确切分子机制尚未完全阐明。c-Myc是一个涉及细胞增殖、分化、上皮-间充质转 ...