UMAP is a powerful tool for exploratory data analysis, but without a clear understanding of how it works, it can easily lead ...

A recent study delves into the pivotal role of Setd2, a histone methyltransferase enzyme, in embryonic development within mice.

Researchers developed spatial aging clocks to map brain cell aging, revealing how T cells accelerate aging and NSCs ...

In a study recently published in Science, lab leader Junyue Cao and his team employed single-cell sequencing to analyze over 21 million cells from all major organs of mice at five distinct life stages ...

A new study from Karolinska Institutet maps the cellular and molecular dynamics of human wound healing in exceptional detail.

RNA sequencing and single-cell RNA sequencing analyses of the yolk sac and embryos revealed significant ... may still be exerted by the CD Setd2 protein in specific developmental contexts. This ...

Their findings enhance our understanding ... New Drug Tested to Reduce Side Effect of 'Half-Matched' Stem Cell Transplants Dec. 5, 2024 — Stem cell transplantation is used to treat several types ...

Created by computational biologist Bo Wang and his team at the University of Toronto, the single-cell generative pretrained transformer (scGPT) can analyze single-cell RNA sequencing data more ...

This manuscript provides valuable information about the genesis of CPSF6 condensates due to HIV-1 infection. However, the evidence is incomplete as it is missing more functional assays. Furthermore, ...

Overall, this fundamental study identified a novel role of NOLC1 in regulating p53 nuclear transcriptional activity and p53-mediated ferroptosis in gastric cancer. The evidence supporting the ...