Our objective of this study was to elucidate the molecular and inflammatory mechanisms by which CD39 activity modulates atherosclerosis Approach and Results: Here we identify that the genotype of SNP ...

As an important regression factor in cardiovascular diseases, regulatory CD4+ Foxp3+T cells (Tregs) are a highly oxidative lymphocyte subset, and Tregs heavily rely on fatty acids to fuel their ...

T1D的关键发病机制是调节性T细胞（Tregs）和效应T细胞（Teffs）的稳态失衡，调控T细胞免疫稳态，实现病因治愈是本领域亟待解决的科学难题。

These data validate the understanding that Tregs are enhanced only at lower IL-2 levels, whereas higher IL-2 levels reduce Treg function. There is an inverse relationship, if you will, between ...