Our objective of this study was to elucidate the molecular and inflammatory mechanisms by which CD39 activity modulates atherosclerosis Approach and Results: Here we identify that the genotype of SNP ...

Although the immune suppression function of CXXC1 KO Treg is comparable to WT Treg in an in vitro assay, these KO Tregs failed to suppress autoimmune diseases such as EAE and colitis in Treg transfer ...

I believe the opportunities ahead of us in 2025 and beyond are what investors, stockholders, and patients should be most excited about. Our science and approach of regulating Tregs is now validated in ...