The US Food and Drug Administration had just approved VNS in 2005 for the long-term adjunctive treatment of chronic or recurrent depression in adults who had had inadequate responses to at least ...
Depression is considered treatment-resistant after multiple types of medications, used singly and in various combinations, fail to significantly improve symptoms or create side effects that are ...
Treatment-resistant depression (TRD) occurs when major depressive disorder (MDD) treatment does not work. There is no official definition or set criteria for TRD, but the measure often used is an ...