Endothelial cells are also likely to participate in activation, both by production of cellular fibronectin and via conversion of transforming growth factor (TGF)-beta from the latent to active ...

CAR-T cells are genetically engineered T-cells with synthetic receptors that recognise a ... integrin inhibitor abituzumab and anti-PD-L1/TGF beta trap M7824, both in phase II.

remains unanswered. Currently, it is not possible to identify individuals at risk of developing Crohn disease, and current molecular tools, such as genetic markers (nucleotide-binding oligomerisation ...