Understanding, let alone fighting, something so infinitesimally small is a crowning challenge of modern medicine. The physical structure of its molecules dictates how a virus infects people and moves ...
Research interests: assembly and structure determination of viruses, virus-receptor interaction, antivirals, neutralizing antibodies, electron cryo-microscopy, image processing, crystallography. Sarah ...
The dengue virus has a roughly spherical shape. Inside the virus is the nucleocapsid, which is made of the viral genome and C proteins. The nucleocapsid is surrounded by a membrane called the ...
In most people, the lung-infecting pathogens known as respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) ...
For vaccinia virus, ER wrapping around the viral replication ... structures are located in only one small part of the vesicle structure, in most EM profiles they could look closed.
The central dogma of biology defines the flow of genetic information: It describes how proteins are made from mRNA templates, ...
The measles virus is an enveloped virus bearing a lipid bilayer. The bilayer holds the receptor binding hemagglutinin (H) protein and the fusion (F) protein. For infection to happen, the H protein ...