Tumor cells transform fibroblasts into cancer-associated fibroblasts, which have an important immunosuppressive activity on which growth, invasion, and metastasis depend. These activated fibroblasts ...
Given the vital role of such cellular crosstalk interactions in regulating tissue homeostasis and repair, it had been speculated that dysregulated stromal-immune communication is a key pathogenic ...
Endometriosis is a debilitating disease affecting 190 million women worldwide and the greatest single contributor to infertility. The most broadly accepted etiology is that uterine endometrial cells ...
Tissue vaccines include antigens associated with neoplastic cells and with the tumor stroma. Furthermore, they include antigens that may be expressed only following in vivo growth versus growth in ...
Invasive cells with these protrusions expand out in to the surrounding tissue stroma (arrows). The green structure on the top of the movie frame is the kidney duct. The intestine is below the ...
They are sometimes called atypical proliferative tumours or tumours of low malignant potential. They are different to ovarian cancer because they don't grow into the supportive tissue of the ovary ...