Loss of HOIP prevents formation of M1-Ub chains and reduces STING-induced NF-κB and IRF3 signaling in human THP1 monocytes and mouse bone marrow-derived macrophages, without affecting STING activation ...

For most people, a bee sting is just a nuisance that may cause temporary pain and itching at the sting site. Home remedies can help, but you should seek immediate medical attention if there are ...

Ins ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, announced that it has received IND clearance from FDA for ISM5939, a potential best-in-class ...

The cGAS-STING pathway begins with an enzyme called cGAS-sensing double-stranded DNA present in the cytosol. It triggers a molecular messenger called cGAMP, which activates a protein called STING.

Filled with the top stories to start your day, and emergency news alerts.

The Signal is produced by senior students at the University of King’s College School of Journalism, Writing & Publishing.

where genomic data was combined with proteomic testing to study the PI3K/AKT/mTOR pathway, a frequently disrupted signaling pathway in breast cancer. The study highlights how integrating genomic ...

For we are labourers with God: ye are God's husbandry, ye are God's building (1 Corinthians 3:9). The Bible does not say we are labourers for God, but we are labourers (fellow-workers) with God. He ...

Cellular signal boosters use big antennas to improve coverage in your home or car. These are the top signal boosters for apartments, houses, and vehicles. I’m one of PCMag’s mobile analysts.