The authors apply their protocol to investigating heterogeneity in a biofilm model of E. coli, and convincingly show how their technology can detect minority subpopulations within a complex community.

The authors apply their protocol to investigating heterogeneity in a biofilm model of E. coli, and convincingly show how their technology can detect minority subpopulations within a complex community.

In this feature, we explore the impacts of technical variability in single-cell experiments and how standardisation might be ...

Here we propose a method that integrates FACS-based 5’-end single-cell RNA sequencing (FB5P-seq) and monoclonal antibody cloning for integrative ... Libraries were then prepared according to the ...

Then, scientists can analyze the composition of RNA molecules that contain codes for building new proteins. "However, typical single-cell sequencing experiments use what is called short-read ...

scplotter is an R package that is built upon plotthis. It provides a set of functions to visualize single-cell sequencing data in an easy and efficient way.

Background: Acute myeloid leukemia (AML) is a hematologic tumor with poor prognosis and significant clinical heterogeneity. By integrating transcriptomic data, single-cell RNA sequencing data and ...

Community-curated list of software packages and data resources for single-cell, including RNA-seq, ATAC-seq, etc.

Researchers developed spatial aging clocks to map brain cell aging, revealing how T cells accelerate aging and NSCs ...