UK: A recent retrospective cohort study has highlighted the critical role of kidney function in patients diagnosed with ...

Renal amyloidosis usually manifests as proteinuria, often resulting in nephrotic syndrome, but rarely presents as progressive renal failure. The heart is affected pathologically in up to 90% of ...

Transthyretin amyloid cardiomyopathy (ATTR-CM) is a progressive cardiomyopathy that commonly presents with concomitant chronic kidney disease. Chronic kidney dysfunction is associated with worse ...

In this retrospective cohort study, decline in kidney function was frequent in patients with transthyretin amyloid cardiomyopathy (ATTR-CM) and was consistently associated with an increased risk of ...

Preclinical studies have shown AT-02 is able to bind to multiple amyloid types and can induce macrophage mediated amyloid phagocytosis and removal. The Food and Drug Administration has granted Orphan ...

Of these, 5 had renal biopsy–confirmed renal AL amyloidosis, and 1 had LCDD. All 5 patients with AL amyloidosis had λ Bence Jones proteinuria. The only patient in our study with renal LCDD had ...

Background: Transthyretin cardiac amyloidosis (ATTR-CA) is a progressive cardiomyopathy that commonly presents with concomitant chronic kidney disease. Impaired renal function is associated with worse ...

Discover how kidney function decline in ATTR-CM patients predicts higher mortality, highlighting its role as a critical marker in disease management and care optimisation.

One of the most serious complications of rheumat0logic and autoimmune diseases can be prevented with biologic drugs, a single-center chart review suggested, and some such products may be more ...