AKT signaling pathway is one of the most critical and extensively investigated signaling pathways. It is the central ...

Data demonstrate potential superiority of a targeted protein degradation strategy compared to kinase inhibition for both BTK ...

InnoCare Pharma (HKEX: 09969; SSE: 688428), a leading biopharmaceutical company focusing on the treatment of cancer and autoimmune diseases, today announced that the first subject has been dosed in ...

Key proteins, such as suppressor of cytokine signaling (SOCS3) and protein-tyrosine phosphatase 1B (PTP1B), inhibit ... When ...

Researchers used base and prime editing to uncover new EGFR gene mutations that affect cancer progression and drug resistance ...

Tyrosine phosphorylation is an essential protein ... such as the Epidermal Growth Factor Receptor and the Insulin Receptor. Besides its role in the regulation of insulin signaling, PTP1B also plays an ...