New research has revealed the diverse assembly and regulation of Type-A GABA receptors (GABAARs), which are crucial for ...

G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

GC-A is a type of single-pass transmembrane receptor protein that spans the cell membrane, connecting a binding region on the cell surface to an interior signaling domain, allowing it to transmit ...

A team of microbiologists and virologists at Wuhan University, working with colleagues from the Chinese Academy of Sciences, ...

GC-A is a type of single-pass transmembrane receptor protein that spans the cell membrane, connecting a binding region on the cell surface to an interior signaling domain, allowing it to transmit ...

This analysis revealed that lung vitamin D receptor expression is downregulated in patients with PAH. These findings were confirmed by comparing messenger ribonucleic acid (mRNA) and protein ...

Researchers from the Institute for Neurosciences (IN), a joint center of the Miguel Hernández University of Elche (UMH) and ...

Human epidermal growth factor receptor 2 (HER2) proteins are found on the surface of breast cells and are involved in normal cell growth. Too much HER2 protein, however, can cause some types of breast ...

Most cancer treatments – from chemotherapies to engineered immune cells – have a host of side effects, in large part because they affect healthy cells in the body at the same time as targeting tumor ...

This bioinformatics-assisted review describes key biological elements of known pathways, such as the forkhead box protein ...

A healthy brain balances "activate" and "inhibit" signaling in its neural microcircuitry, with the inhibitory signaling often provided by cell ...