引言人类大脑是人类智力起源和演化的结构基础，在几百万年的演化历程中人类的脑容量显著扩大，这也是人类区别于其他物种的重要特征之一。在演化发育生物学的视角下，物种之间的演化差异在器官发育过程中展现和被选择。因此，人类脑容量的扩增是由于人类演化出了独特的大 ...

Stem cells are specialized cells that have the potential to develop into not one but many different types of cell. They are unlike any other cell for three specific reasons: They are unspecialized, ...

This work paves the way for further research to exploit these findings and leverage lineage reprogramming of glia into subtype specific neurons as a new therapeutic avenue." More information ...

"Zebrahub" is an atlas of cells in developing zebrafish embryos, and scientists say it will help us learn about our own biology, too. When you purchase through links on our site, we may earn an ...

Recent studies suggest that when neurons are overwhelmed by oxidative stress, they spew out toxic, peroxidated lipids. Glia then sail in to mop up the spill, containing the oils within intracellular ...

In the brain, one way that neurons communicate with one another is through secretion of glutamate. Astrocytes, a type of glial cell, mop up extra glutamate, convert it to glutamine—the precursor for ...

Imaging results also validated SE conformation emergence during the differentiation of radial glia (RG) to excitatory neurons. Chromatin compartmentalization strength scores inversely correlated ...

Cortical formation in the developing brain is a highly complicated process involving neuronal production (through symmetric or asymmetric cell division) interaction of radial glia with neuronal ...

One of their major efforts was the study of laminin receptors on Schwann cells, the myelinating peripheral glia. By generating and comparing animal models of demyelinating neuropathies to patient's ...

Experience governs neurogenesis from radial-glial neural stem cells (RGLs) in the adult hippocampus to support memory. Transcription factors (TFs) in RGLs integrate physiological signals to dictate ...