Researchers have cooked up a new way to improve mRNA delivery, developing an optimal 'recipe' for ionizable lipids - key ingredients in lipid nanoparticles, the molecules behind the COVID-19 vaccines ...
On its own, RNA is fragile, and would otherwise dissolve without ever reaching its intended ... This switch is essential for the nanoparticle's journey: In the bloodstream, ionizable lipids stay ...
A multi-institutional team of researchers, led by Georgia Tech's Francesca Storici, has discovered a previously unknown role for RNA. Their insights ...