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17 小时
Therapeutic cancer vaccine may improve tumor response to immune checkpoint blockade treatments
Immune checkpoint blockade (ICB) therapies can be very effective against some cancers by helping the immune system recognize ...
labiotech
17 小时
Seven miRNA-focused companies pioneering new therapies in 2024
Delve into the field of miRNA with 7 promising companies with miRNA-focused candidates in the pipeline, from oncology to neurodegeneration.
GEN
4 天
snoRNA Target Discoveries Could Lead to Potential Therapeutic Strategies
A new approach for identifying new cellular RNA targets of snoRNAs uncovered thousands of previously unknown targets ...
labiotech
4 天
Can AlphaFold3’s open-source platform revolutionize the way we discover drugs?
Find out how Google DeepMind's AlphaFold3 platform could help scientists revolutionize the field of drug discovery.
technologynetworks
4 天
Cellular Protein Used as a Pawn by Hepatitis A Virus To Infect Liver Cells
New research has illustrated how hepatitis A virus uses cellular proteins, like PDAP1, to infect liver cells, replicate and ...
The EMBO Journal
5 天
Structural insight into Okazaki fragment maturation mediated by PCNA-bound FEN1 and RNaseH2
However, the temporal relationships and functional modulations between these PCNA-binding proteins are unclear. Here, we developed a strategy to purify endogenous PCNA-containing complexes from native ...
5 天
Scientists implicate a novel cellular protein in hepatitis A infection
Viruses have thrived in humans for tens of thousands of years, evolving to take advantage of the machinery of cells to ...
5 天
Plant biologists uncover surprising ways transcription factors regulate plant development
Within all complex, multicellular living systems such as plants and humans, there exists a set of genetic elements that can ...
BioPharma Dive
11 天
How a Biogen drug set the stage for a new biotech targeting ALS
Trace Neuroscience, which launched this week with $101 million, benefited from last year’s approval of Qalsody. Its CEO spoke ...
The Scientist
14 天
How Stem Cells Stay Young
ABOVE: Hematopoietic stem cells have mechanisms in place to generate intrinsically disordered proteins, which could underlie ...
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