Itching is a common symptom of chronic liver diseases. Treatment options include avoiding scratching, using mild soaps, applying topical creams, taking prescription oral medications, and more.
Histamines are chemicals in the body that cause allergy symptoms, including itching. An antihistamine is a common treatment for allergic reactions. But many antihistamine drugs can make you sleepy ...
Of the 510,000 PBC patients, 240,000 will experience cholestatic pruritus. The FDA granted linerixibat orphan drug designation in the treatment of PBC and associated cholestatic pruritus in 2019.
Many patients attribute poor sleep, depression, agitation, difficulty concentrating, and reduced sexual desire and function to itch. Treatment can be challenging, and often several modalities are ...
Treatment with liberixibat led to a statistically significant improvement in itch compared with placebo. Topline results were announced from a phase 3 trial evaluating linerixibat for the ...