Published reports on placebo-controlled clinical trials and other studies investigating the use of pure opioid antagonists for the prevention and treatment of opioid-induced pruritus (OIP ...

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PBC patients receiving linerixibat saw statistically significant improvement in cholestatic pruritus - or relentless itch.

In the three aforementioned studies of epidural delivery of naloxone in combination with an opioid (fentanyl or morphine), the frequency of pruritus was decreased, with no reversal of analgesia noted.

Itching of the skin, also called pruritus, is a common problem experienced by many people. The itching may or may not come along with a rash, which can be limited to small areas of skin or can occur ...

Cholestatic pruritus is a common symptom of primary biliary cholangitis (PBC), a rare autoimmune liver disease. Researchers are looking to establish the safety and efficacy of linerixibat – an ...

Treatment with liberixibat led to a statistically significant improvement in itch compared with placebo. Topline results were announced from a phase 3 trial evaluating linerixibat for the ...

Background: Pruritus ani (PA), a neurofunctional dermatosis, is one of the most common complications of hemorrhoids, which seriously affects the quality of life of patients. Medical hemorrhoid gel ...

Adverse food reactions in dogs are a multifaceted issue involving immune-mediated hypersensitivities or non-immunologic food ...

(Getty Images) Among 227 adult participants at baseline, 42% had moderate pruritus and 58% had severe pruritus. The most common prior pruritus therapies were antihistamines (15%), bile acid-binding ...

Galderma has reported that the randomised Phase III OLYMPIA 1 trial, which evaluated the nemolizumab monotherapy in adult ...