Joshua K. Sabari, MD, describes the mechanism of action of lurbinectedin as a synthetic alkaloid that binds to guanine residues in the minor groove of DNA, forming adducts that disrupt DNA repair ...

Mechanism of action describes the process by which a molecule, such as a drug, functions to produce a pharmacological effect. A drug’s mechanism of action may refer to its effects on a ...

The question of putative mechanisms of action continues to haunt psychopharmacology. Put simply, we know these drugs work, but we have very little idea how. We make guesses based on the ...

Praluent (alirocumab) is a brand-name subcutaneous injection that’s prescribed for high cholesterol and lowering certain risks. Praluent isn’t known to interact with other drugs or supplements ...

Sanofi and Regeneron’s Praluent may still not be cost effective compared to other cholesterol-lowering drugs despite a recent price cut, a new study has claimed. The drug's high price point has ...

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When I think of a tough little camera built to capture action, GoPro naturally comes to mind, doesn’t it? GoPro pioneered the action camera concept, and while they’ve dominated the space for years, ...

If you need an adventure-proof camera to capture your daring exploits, try one of the best action cameras. Based on our in-depth tests, each of the options featured below has a unique set of ...

See our ethics statement. The action genre had a fantastic 2023, with strong new entries in banner franchises and exciting one-off movies from creators established and upcoming alike. 2024 is ...

Amazon Prime Video is one of the best streamers when it comes to action. For a streamer, there’s no better position to be in than having some of the best action movies anywhere, including almost ...