Monoclonal antibodies are novel therapeutic agents used with great success in the treatment of rheumatoid arthritis (RA). Different parts of the immune system have been targeted by monoclonal ...
Most discontinued anti-tau antibodies (red) targeted tau’s N-terminus. Of the antibodies currently in trials (green), bepranemab and E2814 presented results at CTAD, while JJ-63733657/posdinemab and ...
Laflamme is part of a growing community that wants to solve the problem of unreliable antibodies in research. He teamed up with molecular geneticist Aled Edwards at the University of Toronto ...
In the case of Archon, the customizable parts are small, computationally designed proteins that bind to antibodies, causing them to cluster and form into the cage structures. The science behind ...
They both targeted a part of the protein known as CIDRα1 which interacts with the EPCR receptor." The team then needed to test if those antibodies could also successfully block EPCR binding in ...
Investigators led by Pablo Penaloza-MacMaster, Ph.D., associate professor of Microbiology-Immunology, have discovered that administering an antibody treatment four days after mRNA vaccination ...
The antibody molecules circulating in our blood and known to immunologists as IgG (the acronym stands for “immunoglobin G”) are roughly Y-shaped. The Y’s horns are customized to cling to specific ...