29, 2024 — Mechanical engineers designed a 3D-printed femur that could help doctors prepare for surgeries to repair bones and develop treatments for bone tumors. The study, which focused on the ...

Osteolytic diseases, such as osteoporosis, rheumatoid arthritis, osteosarcoma, and giant-cell tumors of bone, are characterized by increased bone resorption and decreased bone formation, leading to ...

It has become increasingly clear that bone cells, osteoblasts, osteoclasts, and osteocytes, communicate and regulate the fate of each other through RANK/RANKL/OPG, liver X receptors (LXRs), ...

In this study, our results uncover the function and mechanism of CHMP5 in the regulation of cell senescence and bone formation in osteogenic cells. Deletion of Chmp5 causes endolysosomal dysfunction ...

The main difference between a bone fracture and a bone bruise is its severity. Bone bruises are far less severe and involve less tissue damage. With that said, there is often a fine line between what ...

Direct stimulation of osteoblasts by parathyroid hormone has not led ... anatomical sites and was characterised by the formation of new cortical bone. While in most patients treated with ADA/MTX an ...

Bone tissue is composed of cells, namely osteoblasts, osteoclasts and osteocytes, and an extracellular matrix comprising inorganic hydroxyapatite crystals and organic collagen.

Zoledronic acid is a potent, new-generation bisphosphonate indicated for the treatment of documented bone metastasis in patients with solid tumors and bone lesions associated with multiple myeloma.

July 1, 2024 — Multiple myeloma is one of the most common forms of cancer of the immune cells in the bone marrow. It is considered incurable. Even when patients respond to treatment at first ...