"We first carried out simple ex vivo experiments by isolating the optic nerve of adult mice and placing it into culture," ...

The hypothesis that it disrupts the function of retinal ganglion cell axons by increasing mechanical forces on the lamina cribrosa of the optic nerve head has received considerable experimental ...

Bipolar cells in turn connect to amacrine cells and ganglion cells, the latter having axons that bundle together to form the optic nerve ... both neuronal and glial cells. This was shown clearly ...

However, optic nerve regeneration and restoration of vision in patients with glaucoma is still far from reality. Neuroprotective approaches in the form of gene therapy may provide significant ...