In this valuable study, the authors used an elegant genetic approach to delete EED at the post-neural crest induction stage. The usage of the single-cell RNA-seq analysis method is extremely suitable ...

Direct reprogramming of one cell type to another may not be probabilistic, but deterministic, suggests a study focused on ...

A University of Toronto study reveals that neural crest stem cells, found in the skin and other areas, are responsible for the generation of reprogrammed neurons, contradicting the prevailing theory ...

Neural crest stem cells may have gone unnoticed by others studying cell reprogramming because, while they are widespread ...

Researchers found that neural crest stem cells are uniquely capable of reprogramming, challenging current reprogramming theories and opening possibilities for stem cell-based treatments. A research ...

The research team proposes a new theory, one that suggests there is one unique type of stem cell that can be reprogrammed into different cell types. "We believed that most cases of cell reprogramming ...

“Neural crest stem cells may have gone unnoticed by others studying cell reprogramming because, while they are widespread throughout the body, they are also rare,” said Derek van der Kooy ...

More information: Justin J. Belair-Hickey et al, Neural crest precursors from the skin are the primary source of directly reprogrammed neurons, Stem Cell Reports (2024). DOI: 10.1016/j.stemcr.2024 ...

They specifically looked at genes regulating a stem cell population called the neural crest, which is only found in ...

A recent study explores how MYCN-driven neuroblastoma hijacks the m6A modification process to prevent proper cell ...

We work in two areas. The first is traditional cell and molecular biology, focussed on the molecular mechanisms underlying mesoderm formation, and neural crest induction, and tissue and organ ...