ANCAs recognize other epitopes than PR-1; T-cell lines established from PR-3/ANCA-positive patients with Wegener's disease do not recognize T2 cells pulsed with PR-1; Normal myeloid cells ...

Kura Oncology, Inc. and Kyowa Kirin Co. Ltd.’s selective oral menin inhibitor ziftomenib showed encouraging data across ...

Cathepsin G (CTSG) is overexpressed and aberrantly localized for antigen presentation on acute myeloid leukemia blasts and stem cells compared to normal hematopoietic progenitors. Earlier this year, ...

Epilepsy, the most common neurological disorder, is characterized by seizures resulting from an imbalance between brain ...

Mitochondria are pivotal cellular organelles that play a crucial role in regulating metabolism and cell survival, making them ...

Continuing its role as a leader in leukemia research, Washington University School of Medicine in St. Louis has been awarded ...

Call to Christian dedication; proper use of liberty in Christ; the example of Christ's suffering. But if, when ye do well, and suffer for it, ye take it patiently, this is acceptable with God. For ...

Iadademstat is a small molecule commercialized by Oryzon Genomics, with a leading Phase II program in Neuroendocrine Carcinoma.

However, our understanding of how gradual changes in gene dosage affect molecular, cellular, and organismal traits is currently limited. To address this gap, we induced gradual changes in gene ...

Istisociclib is a small molecule commercialized by Kronos Bio, with a leading Phase II program in Germ Cell Tumors;Uterine Cancer;Epithelial Ovarian Cancer.

Abstract published as part of the American Society of Hematology (ASH) Annual Meeting Study shows Annamycin effectively targets both Cytarabine (Ara-C) and Venetoclax resistant acute myeloid leukemia ...