while mucosal epithelial damage is more severe owing to a lack of compensation by the weakly expressed Dsg1. In mucocutaneous pemphigus vulgaris, antibodies against both Dsg1 and Dsg3 are produced ...

My current research project uses stem cell organogenesis to examine H. pylori infection in the human stomach and determine whether infection upregulates epithelial ST6Gal-I expression, a ...

and how epithelial-cell-derived factors, through effects on dendritic cells (DCs) and lymphocytes, regulate intestinal immune homeostasis. One of the oldest known components of mucosal immunity ...

The nanoscale systems have to penetrate or diffuse through the mucosal membrane to reach the epithelium as depicted in Figure 3A & B. The mucosal surfaces are lined by epithelial cells ...

Villi are found in the innermost layer of your intestine, known as the mucosa. Epithelial cells make up the villi, and ...

By understanding more about the cycle of inflammation, it might be possible to find new ways to prevent or treat this in IBD.