Primary intestinal epithelial cells have a very short lifespan in vitro when cultured free of mucosal elements. Support of the basal plasma membrane by a more natural substrate may thus enhance the ...

Background—The functions of urokinase in intestinal epithelia are unknown. Aims—To determine the relation of urokinase expressed by intestinal epithelial cells to their position in the ...

while mucosal epithelial damage is more severe owing to a lack of compensation by the weakly expressed Dsg1. In mucocutaneous pemphigus vulgaris, antibodies against both Dsg1 and Dsg3 are produced ...

Hence vaccinated individuals are still susceptible to infection/illness and transmission. Intranasal vaccinations have the potential to induce mucosal immunity at the nasal epithelium (primary site of ...

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Components of the intestinal mucosal mechanical barrier. The mechanical barrier is made up of the mucus layer, intestinal epithelial cells, tight junctions between cells and the mucosal lamina ...

Sodium butyrate modulates necroptosis in intestinal epithelial cells during liver cirrhosis, offering potential therapeutic ...

The COVID-19 virus spreads via mucus once inside an infected airway, allowing it to reach into the lower lungs, according to ...

By understanding more about the cycle of inflammation, it might be possible to find new ways to prevent or treat this in IBD.