Here, authors visualize impaired ATP recovery in podocytes in a murine model of ischemic AKI using intravital ATP imaging and propose accelerated mitochondrial fission as a key factor of ischemic ...

Methods—Electron microscopy and subcellular organelle marker enzyme studies were done in rat small intestine after oral administration of indomethacin (doses varied between 5 and 30 mg/kg). The effect ...

Our study reveals, at a molecular level, how the mitochondrial RNase Z complex recognizes and processes tRNA molecules. By ...

New research uncovers how mitophagy, the cellular recycling of damaged mitochondria, changes dynamically in the aging ...

TEM acquires Ambry Genetics, expanding its testing portfolio and redefining precision medicine. CHICAGO, November 25, 2024--Tempus AI, Inc. (NASDAQ: TEM), a technology company leading the adoption ...

“Our study reveals, at a molecular level, how the mitochondrial RNase Z complex recognizes and processes tRNA molecules,” said Genís Valentín Gesé, the first author of the study. “By using advanced ...

Mitophagy dynamics change with age, particularly during midlife, influencing brain health and aging. These findings offer ...

In this study, our results uncover the function and mechanism of CHMP5 in the regulation of cell senescence and bone formation in osteogenic cells. Deletion of Chmp5 causes endolysosomal dysfunction ...