The articles in this Focus explore the molecular mechanisms that induce cell senescence, functional consequences for surrounding tissues, emerging therapies to counteract senescent-associated ...

Their findings, published in Developmental Cell, shed light on how a protein called CDK5RAP2 activates the microtubule ...

A study from researchers at IRB Barcelona and CNIO has unveiled the role of CDK5RAP2 in activating the γ-tubulin ring complex (γTuRC), a vital component for microtubule formation in cells. By using ...

For the first time, researchers have discovered that the accumulation of aged and failing cells, called senescent cells, in one diseased organ can spread to multiple healthy organs, causing them ...

Mayo Clinic researchers have found that senescent cells—non-dividing "zombie" cells—accumulate in the skin as people age and may influence aging in other parts of the body. Their recent study ...

Mayo Clinic researchers in the United States have found that senescent cells – non-dividing “zombie” cells – accumulate in the skin as people age and may influence ageing in other parts of ...

Mayo Clinic researchers have found that senescent cells — non-dividing “zombie” cells — accumulate in the skin as people age and may influence aging in other parts of the body. Their ...

It oxidizes and damages DNA, fatty acids, and biological membranes, etc. Generally, senescent cells have irreversibly stopped proliferating, are resistance to cell death, and tend to accumulate in the ...

In the course of their study, the researchers found that diseases associated with aging and obesity are triggered and progress when senescent cells accumulate in internal organs, blood vessels and ...