Additionally, the target dose of metoprolol tartrate was 50 mg b.i.d. in contrast to the 200 mg target dose of metoprolol succinate in MERIT-HF. Does this resolve the β-1 vs. β-1 β-2 blockade ...
The disparity in the results between the Metoprolol in Dilated Cardiomyopathy Trial and MERIT-HF raised the possibility that only extended- release metoprolol succinate is effective in treating ...